Businesses for Sale in Durham, North Carolina

About this business

This well-established pizza brand in the Triangle area of North Carolina has a dedicated customer base and a strong community reputation, consistently achieving annual sales exceeding $1M. Despite current profitability challenges, there is great potential for increased margins with more efficient management. An ideal opportunity for a hospitality-savvy individual to take over this high-traffic, established concept. Acquiring a brand presence like this from scratch would be a substantial investment. Contact us for more details.

About this business

Chapmanetics is revolutionizing clinical pharmacy with advanced technology aimed at enhancing medication safety, optimizing drug therapy, and modernizing prescribing decisions. With over 25 years of experience, their innovative platform integrates drug comparison algorithms, dosing intelligence, and medication safety analytics to provide actionable insights for healthcare professionals, positioning them at the forefront of healthcare innovation.

About this business

Own a legendary New York-style pizzeria in the Triangle region of North Carolina, known for its award-winning slices, community support, and prime location with live music entertainment.

About this business

Well-established, multi-location pediatric therapy organization that has served communities across North Carolina for over 40 years. The Company provides clinic-based speech-language therapy, occupational therapy, and feeding therapy through evidence-based methodologies and highly individualized treatment plans. The clinic primarily serves pediatric patients with developmental, neurological, sensory processing, and feeding disorders. Approximately 95% of services are delivered in-clinic, creating strong continuity of care, consistent scheduling, and a structured therapeutic environment. Teletherapy services are available when clinically appropriate, providing flexibility while maintaining quality standards. Over four decades, they have developed a strong regional reputation for clinical excellence and outcomes-driven care.

About this business

This listing is best suited for an operator, entrepreneur, or experienced foodservice professional who values location, speed, and flexibility over acquiring a legacy brand.Rather than paying a multiple on historical earnings, the buyer acquires:A proven QSR destination.Existing build-out and equipmentA high-visibility, high-density trade areaThe ability to introduce a new, differentiated concept tailored to the Durham foody demographic.Average monthly customer count of this listing is best suited for an operator, entrepreneur, or experienced foodservice professional who values location, speed, and flexibility over acquiring a legacy brand.Rather than paying a multiple on historical earnings, the buyer acquires:A proven QSR destination.Inherits over $33,000 in Leasehold Improvements, existing build-out and equipmentA high-visibility, high-density trade areaThe ability to introduce a new, differentiated concept tailored to the Goldbet demographic.Average monthly customer count of 1,503/mo with a check average of $16.37

About this business

Since opening its doors in 2020, this well-established facial and waxing spa has flourished as a beloved part of the downtown community, growing entirely through word-of-mouth and referrals, fueled by strong local support for women-owned businesses. Operating from a home-based studio in the heart of downtown, the business serves a loyal client base of 600 to 700 customers and has continued to expand year after year with minimal advertising—limited to a few boosted Instagram posts during its first year. Recognized on platforms like Reddit and Facebook as a go-to destination for exceptional beauty services, it boasts 37 glowing five-star reviews. This turnkey opportunity is ideal for an esthetician seeking a trusted, profitable book of business with ample room to scale and make it your own.